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Fig. 2 | 3D Printing in Medicine

Fig. 2

From: Creating three dimensional models of Alzheimer’s disease

Fig. 2

Manual segmentation and smoothing of the hippocampus. Example of manual editing of the atlas-based auto-segmentation at the head of the hippocampus. Manual segmentation is performed with images in the sagittal (a), axial (b), and coronal (c) planes. Top row shows raw images with colored squares magnified in second row. Third row shows pixels assigned as hippocampus in gold. Fourth row shows final manual segmentation in red. Fifth row shows both auto-segmentation and manual segmentation with overlap in orange. Solid black arrows show areas where amygdala is auto-segmented as hippocampus. Solid red arrow shows area where the lateral border of the hippocampus is not smoothly assigned in auto-segmentation. Open black arrow shows extra pixels assigned to the dorsal hippocampus border in the auto-segmentation that are outside of hippocampus. Open red arrow shows the manual editing of the medial hippocampus border that included the subiculum

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