Table 1 Clinical characteristics of subjects
From: Creating three dimensional models of Alzheimer’s disease
Classification | Age/Sex | Symptoms | Living arrangement | DRS | FDG-PET | PiB-PET | Tau-PET |
|---|---|---|---|---|---|---|---|
Normal | 54/F | None | Independent | 143 (94%) | (−) | (−) | (−) |
Clinically-Mild AD | 78/M | Mild memory dysfunction. Rarely gets lost driving | Independent | 120 (1%) | Precuneus hypometabolism | (+) | (+) |
Clinically-Moderate AD | 74/F | Memory poor. Gets lost. Reduced daily activity. | Assisted Living | 96 (<1%) | Bilateral parietotemporal hypometabolism | (+) | (+) |
Clinically-Severe AD (Severe-1) | 84/M | Doesn’t recognize family. Needs help dressing and bathing. Incontinent. | Nursing home | 83 (<1%) | Bilateral frontal, parietal, temporal hypometabolism | (+) | (+) |
AD with radiologically severe hippocampal atrophy (Severe-2) | 81/M | Severe memory loss. Gets lost driving and in home. | Independent | 112 (<1%) | Bilateral parietotemporal, lateral occipital, precuneus, and posterior cingulate hypometabolism | (+) | (+) |