Articles

3D printing of nanocomposite pills through desktop vat photopolymerization (stereolithography) for drug delivery reasons

The desktop vat polymerization process or stereolithography printing is an ideal approach to develop multifunctional nanocomposites wherein a conventional solid dosage form is used as a reservoir for compliant...

Authors: Peeyush Kumar Sharma, Dinesh Choudhury, Vivek Yadav, U. S. N. Murty and Subham Banerjee

A computational fluid dynamics assessment of 3D printed ventilator splitters and restrictors for differential multi-patient ventilation

The global pandemic of novel coronavirus (SARS-CoV-2) has led to global shortages of ventilators and accessories. One solution to this problem is to split ventilators between multiple patients, which poses the...

Authors: Daniel J. Duke, Alexander L. Clarke, Andrew L. Stephens, Lee Djumas and Shaun D. Gregory

Design, inverted vat photopolymerization 3D printing, and initial characterization of a miniature force sensor for localized in vivo tissue measurements

Tissue healthiness could be assessed by evaluating its viscoelastic properties through localized contact reaction force measurements to obtain quantitative time history information. To evaluate these propertie...

Authors: Shashank S. Kumat and Panos S. Shiakolas

Correction to Acknowledgement

Authors:

An open-access and inexpensive 3D printed otoscope for low-resource settings and health crises

Limited access to key diagnostic tools is detrimental to priority health needs of populations. Ear pain, tenderness, itching, and different degree of hearing loss are common problems which require otoscopy as ...

Authors: Matteo Capobussi and Lorenzo Moja

3D printed customised external cranial plate in a patient with syndrome of trephined: ‘a case report’

Syndrome of the trephined is a well-recognised phenomenon that occurs in patients following a craniectomy. It is associated with several symptoms, including headaches, motor impairments, cognitive disorders an...

Authors: Mee H., Greasley S., Whiting G., Harkin C., Oliver G., Marsden D., Andrews R., Sireau S., Price RD., Anwar F., Timofeev IS., Hutchinson PJ., White PA. and Helmy A.

A workflow to generate patient-specific three-dimensional augmented reality models from medical imaging data and example applications in urologic oncology

Augmented reality (AR) and virtual reality (VR) are burgeoning technologies that have the potential to greatly enhance patient care. Visualizing patient-specific three-dimensional (3D) imaging data in these en...

Authors: Nicole Wake, Andrew B. Rosenkrantz, William C. Huang, James S. Wysock, Samir S. Taneja, Daniel K. Sodickson and Hersh Chandarana

Design and 3D-printing of MRI-compatible cradle for imaging mouse tumors

The ability of 3D printing using plastics and resins that are magnetic resonance imaging (MRI) compatible provides opportunities to tailor design features to specific imaging needs. In this study an MRI compat...

Authors: Deborah L. Donohoe, Katherine Dennert, Rajeev Kumar, Bonnie P. Freudinger and Alexander J. Sherman

Use of patient specific 3D printed neurovascular phantoms to simulate mechanical thrombectomy

The ability of the patient specific 3D printed neurovascular phantoms to accurately replicate the anatomy and hemodynamics of the chronic neurovascular diseases has been demonstrated by many studies. Acute occ...

Authors: Kelsey N. Sommer, Mohammad Mahdi Shiraz Bhurwani, Vincent Tutino, Adnan Siddiqui, Jason Davies, Kenneth Snyder, Elad Levy, Maxim Mokin and Ciprian N. Ionita

3D printed composite model of pelvic osteochondroma and nerve roots

3D-printing has become increasingly utilized in the preoperative planning of clinical orthopaedics. Surgical treatment of bone tumours within the pelvis is challenging due to the complex 3D bone structure geom...

Authors: Olivia Fox and Andrew Kanawati

3-D generated anatomic custom talar cement spacers: case reports, technical tips and literature review

With today’s expanding use of total ankle arthroplasty, the ever-present trauma patient, and patients with uncontrolled comorbid conditions, surgeons face significant challenges for lower extremity reconstruct...

Authors: Kimberly K. Broughton, Bonnie Chien, Derek Stenquist, Caroline Williams, Christopher P. Miller and John Y. Kwon

Does vaporized hydrogen peroxide sterilization affect the geometrical properties of anatomic models and guides 3D printed from computed tomography images?

Material extrusion is used to 3D print anatomic models and guides. Sterilization is required if a 3D printed part touches the patient during an intervention. Vaporized Hydrogen Peroxide (VHP) is one method of ...

Authors: Mauricio Toro, Aura Cardona, Daniel Restrepo and Laura Buitrago

Compliant vascular models 3D printed with the Stratasys J750: a direct characterization of model distensibility using intravascular ultrasound

The purpose of this study is to evaluate biomechanical accuracy of 3D printed anatomical vessels using a material jetting printer (J750, Stratasys, Rehovot, Israel) by measuring distensibility via intravascula...

Authors: Adam J. Sparks, Cody M. Smith, Ariana B. Allman, Jillian L. Senko, Karen M. Meess, Richard W. Ducharme, Michael E. Springer, Muhammad Waqas and Adnan H. Siddiqui

Point-of-care 3D printing: a low-cost approach to teaching carotid artery stenting

Carotid Artery Stenting (CAS) is increasingly being used in selected patients as a minimal invasive approach to carotid endarterectomy. Despite the long standing tradition of endovascular treatments, visual fe...

Authors: Pieter De Backer, Charlotte Allaeys, Charlotte Debbaut and Roel Beelen

3D models improve understanding of congenital heart disease

Understanding congenital heart disease (CHD) is vital for medical personnel and parents of affected children. While traditional 2D schematics serve as the typical approach used, several studies have shown thes...

Authors: Jonathan Awori, Seth D. Friedman, Titus Chan, Christopher Howard, Steve Seslar, Brian D Soriano and Sujatha Buddhe

Design and 3D printing of variant pediatric heart models for training based on a single patient scan

3D printed models of pediatric hearts with congenital heart disease have been proven helpful in simulation training of diagnostic and interventional catheterization. However, anatomically accurate 3D printed m...

Authors: Carina Hopfner, Andre Jakob, Anja Tengler, Maximilian Grab, Nikolaus Thierfelder, Barbara Brunner, Alisa Thierij and Nikolaus A. Haas

Methods of 3D printing models of pituitary tumors

Pituitary adenomas can give rise to a variety of clinical disorders and surgery is often the primary treatment option. However, preoperative magnetic resonance imaging (MRI) does not always reliably identify t...

Authors: Daniel Gillett, Waiel Bashari, Russell Senanayake, Daniel Marsden, Olympia Koulouri, James MacFarlane, Merel van der Meulen, Andrew S. Powlson, Iosif A. Mendichovszky, Heok Cheow, Nick Bird, Angelos Kolias, Richard Mannion and Mark Gurnell

A focused simulation-based optimization of print time and material usage with respect to orientation, layer height and support settings for multi-pathological anatomical models in inverted vat photopolymerization 3D printing

3D printing of anatomical models requires multi-factorial decision making for optimal model manufacturing. Due to the complex nature of the printing process, there are frequently multiple potentialities based ...

Authors: Prashanth Ravi and Victoria C. P. Chen

Innovative design of 3D-printed nasopharyngeal pediatric swab for COVID-19 detection

3-dimensional (3D) printing technology provides a solution to meet the high demand for producing adult nasal swabs. A smaller, more flexible nasopharyngeal swab needs to be developed for children and infants s...

Authors: Ameerah Alazemi, Ghadeer AbdulHussain, Abdullah Alawwam, Ali Al-Shatti, Mohammad Alghounaim, Sulaiman Almazeedi, Sarah Al Youha and Salman Al-Sabah

Needle penetration test - qualifying examination of 3D printable silicones for vascular models in surgical practice

During cardiogenic shock blood circulation is minimal in the human body and does not suffice to survive. The extracorporeal life support system (ECLS) acts as a miniature heart-lung-machine that can be tempora...

Authors: Thore von Steuben, Christoph Salewski, Alexander B. Xepapadeas, Moritz Mutschler and Sebastian Spintzyk

Reusability of autoclaved 3D printed polypropylene compared to a glass filled polypropylene composite

Health care waste can be a costly expenditure for facilities as specific disposal methods must be used to prevent the spread of pathogens. If more multi-use medical devices were available, it could potentially...

Authors: Kristin M. Fischer and Andrew P. Howell

Correction to: Applications of 3D printing in breast cancer management

Authors: Arpine Galstyan, Michael J. Bunker, Fluvio Lobo, Robert Sims, James Inziello, Jack Stubbs, Rita Mukhtar and Tatiana Kelil

Computer-assisted subcapital correction osteotomy in slipped capital femoral epiphysis using individualized drill templates

Subcapital osteotomy by means of surgical hip dislocation is a treatment approach offered for moderate-to-severe cases of Slipped Capital Femoral Epiphysis (SCFE). This procedure is demanding, highly dependent...

Authors: Sima Zakani, Christopher Chapman, Adam Saule, Anthony Cooper, Kishore Mulpuri and David R. Wilson

A review and guide to creating patient specific 3D printed anatomical models from MRI for benign gynecologic surgery

Patient specific three-dimensional (3D) models can be derived from two-dimensional medical images, such as magnetic resonance (MR) images. 3D models have been shown to improve anatomical comprehension by provi...

Authors: Teresa E. Flaxman, Carly M. Cooke, Olivier X. Miguel, Adnan M. Sheikh and Sukhbir S. Singh

Sterilization and sanitizing of 3D-printed personal protective equipment using polypropylene and a Single Wall design

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic during the fall of 2019 and into the spring of 2020 has led to an increased demand of disposable N95 respirators and o...

Authors: Karstan Luchini, Shelly N. B. Sloan, Ryan Mauro, Aspram Sargsyan, Aundrea Newman, Purnadeo Persaud, Daniel Hawkins, Dennis Wolff, Jeff Staudinger and Bradley A. Creamer

Introducing 3D printed models of the upper urinary tract for high-fidelity simulation of retrograde intrarenal surgery

Training in retrograde intrarenal surgery for the treatment of renal stone disease is a challenging task due to the unique complexity of the procedure. This study introduces a series of 3D printed models of up...

Authors: Luca Orecchia, Diego Manfrin, Stefano Germani, Dario Del Fabbro, Anastasios D. Asimakopoulos, Enrico Finazzi Agrò and Roberto Miano

The key role of 3D printing and the new medical sterilizable threads in the development of the translaryngeal Tracheostomy Needle Introducer

Percutaneous tracheostomy is frequently performed in intensive care units in patients who require prolonged mechanical ventilation. The first crucial step for the physician in these procedures is the precise n...

Authors: Alessandro Terrani, Enrico Bassi, Alberto Ornaghi, Giacomo Bellani and Giuseppe Foti

3D-printed saw guides for lower arm osteotomy, a comparison between a synthetic CT and CT-based workflow

Three-dimensional (3D)-printed saw guides are frequently used to optimize osteotomy results and are usually designed based on computed tomography (CT), despite the radiation burden, as radiation-less alternati...

Authors: Koen Willemsen, Mirte H. M. Ketel, Frank Zijlstra, Mateusz C. Florkow, Ruurd J. A. Kuiper, Bart C. H. van der Wal, Harrie Weinans, Behdad Pouran, Freek J. Beekman, Peter R. Seevinck and Ralph J. B. Sakkers

Multi-color and Multi-Material 3D Printing of Knee Joint models

This study reports on a new method for the development of multi-color and multi-material realistic Knee Joint anatomical models with unique features. In particular, the design of a fibers matrix structure that...

Authors: Oliver Grimaldo Ruiz and Yasin Dhaher

Point-of-care manufacturing: a single university hospital’s initial experience

The integration of 3D printing technology in hospitals is evolving toward production models such as point-of-care manufacturing. This study aims to present the results of the integration of 3D printing technol...

Authors: Jose Antonio Calvo-Haro, Javier Pascau, José Manuel Asencio-Pascual, Felipe Calvo-Manuel, Maria José Cancho-Gil, Juan Francisco Del Cañizo López, María Fanjul-Gómez, Roberto García-Leal, Guillermo González-Casaurrán, Manuel González-Leyte, Juan Antonio León-Luis, Lydia Mediavilla-Santos, Santiago Ochandiano-Caicoya, Ramón Pérez-Caballero, Almudena Ribed-Sánchez, Javier Río-Gómez…

Systematic review of three-dimensional printing for simulation training of interventional radiology trainees

Three-dimensional (3D) printing has been utilized as a means of producing high-quality simulation models for trainees in procedure-intensive or surgical subspecialties. However, less is known about its role fo...

Authors: Chase Tenewitz, Rebecca T. Le, Mauricio Hernandez, Saif Baig and Travis E. Meyer

3D printing in neurosurgery education: a review

The objectives of this manuscript were to review the literature concerning 3D printing of brain and cranial vault pathology and use these data to define the gaps in global utilization of 3D printing technology...

Authors: Grace M. Thiong’o, Mark Bernstein and James M. Drake

A guideline for 3D printing terminology in biomedical research utilizing ISO/ASTM standards

First patented in 1986, three-dimensional (3D) printing, also known as additive manufacturing or rapid prototyping, now encompasses a variety of distinct technology types where material is deposited, joined, o...

Authors: Amy E. Alexander, Nicole Wake, Leonid Chepelev, Philipp Brantner, Justin Ryan and Kenneth C. Wang

Application of 3D printing and distributed manufacturing during the first-wave of COVID-19 pandemic. Our experience at a third-level university hospital

3D printing and distributed manufacturing represent a paradigm shift in the health system that is becoming critical during the COVID-19 pandemic. University hospitals are also taking on the role of manufacture...

Authors: Rubén Perez-Mañanes, Sonia García-de San José, Manuel Desco-Menéndez, Ignacio Sánchez-Arcilla, Esmeralda González-Fernández, Javier Vaquero-Martín, Javier Pascau González-Garzón, Lydia Mediavilla-Santos, Diego Trapero-Moreno and José Antonio Calvo-Haro

Applications of 3D printing in breast cancer management

Three-dimensional (3D) printing is a method by which two-dimensional (2D) virtual data is converted to 3D objects by depositing various raw materials into successive layers. Even though the technology was inve...

Authors: Arpine Galstyan, Michael J. Bunker, Fluvio Lobo, Robert Sims, James Inziello, Jack Stubbs, Rita Mukhtar and Tatiana Kelil

Correction to: Urgent need hybrid production - what COVID-19 can teach us about dislocated production through 3d-printing and the maker scene

An amendment to this paper has been published and can be accessed via the original article.

Authors: Sascha Hartig, Sven Duda and Lennart Hildebrandt

Cranioplasty with three-dimensional customised mould for polymethylmethacrylate implant: a series of 16 consecutive patients with cost-effectiveness consideration

Different methods of cranioplasty for the reconstruction of bony skull defects exist. In the absence of the autologous bone flap, a customised manufactured implant may be the optimal choice, but this implant h...

Authors: Erasmo Barros da Silva Júnior, Afonso Henrique de Aragão, Marcelo de Paula Loureiro, Caetano Silva Lobo, Ana Flávia Oliveti, Rafael Martinelli de Oliveira and Ricardo Ramina

Precision of computed tomography and cartilage-reproducing image reconstruction method in generating digital model for potential use in 3D printing of patient-specific radial head prosthesis: a human cadaver study

A prosthetic replacement is a standard treatment for an irreparable radial head fracture; however, the surface mismatch of the commercially available designs is concerned for the long-term cartilage wear. The ...

Authors: Suriya Luenam, Theeraset Bantuchai, Arkaphat Kosiyatrakul, Malee Chanpoo, Kantapat Phakdeewisetkul and Chedtha Puncreobutr

Use of tracheobronchial tree 3-dimensional printed model: does it improve trainees’ understanding of segmentation anatomy? A prospective study

This prospective study investigated whether the use of 3D-printed model facilitates novice learning of radiology anatomy on multiplanar computed tomography (CT) when compared to traditional 2D-based learning t...

Authors: Christian O’Brien, Carolina A. Souza, Adnan Sheikh, Olivier Miguel and Timothy Wood

Comparing cost and print time estimates for six commercially-available 3D printers obtained through slicing software for clinically relevant anatomical models

3D printed patient-specific anatomical models have been applied clinically to orthopaedic care for surgical planning and patient education. The estimated cost and print time per model for 3D printers have not ...

Authors: Joshua V. Chen, Alan B. C. Dang and Alexis Dang

Urgent need hybrid production - what COVID-19 can teach us about dislocated production through 3d-printing and the maker scene

The COVID-19 pandemic has led to large-scale shutdowns in society. This resulted in global supply bottlenecks for medical protective equipment. The so-called Maker Movement recognized this emerging problem ear...

Authors: Sascha Hartig, Sven Duda and Lennart Hildebrandt

Correction to: 3D printed bone models in oral and craniomaxillofacial surgery: a systematic review

An amendment to this paper has been published and can be accessed via the original article.

Authors: Matteo Meglioli, Adrien Naveau, Guido Maria Macaluso and Sylvain Catros

Optimization of community-led 3D printing for the production of protective face shields

As the healthcare system faced an acute shortage of personal protective equipment (PPE) during the COVID-19 pandemic, the use of 3D printing technologies became an innovative method of increasing production ca...

Authors: Peter Chengming Zhang, Yousuf Ahmed, Isra M. Hussein, Edem Afenu, Manon Feasson and Anser Daud

3D - Printed Patient Specific Instrumentation in Corrective Osteotomy of the Femur and Pelvis: A Review of the Literature

The paediatric patient population has considerable variation in anatomy. The use of Computed Tomography (CT)-based digital models to design three-dimensionally printed patient specific instrumentation (PSI) ha...

Authors: Njalalle Baraza, Chris Chapman, Sima Zakani and Kishore Mulpuri

MRI guided procedure planning and 3D simulation for partial gland cryoablation of the prostate: a pilot study

This study reports on the development of a novel 3D procedure planning technique to provide pre-ablation treatment planning for partial gland prostate cryoablation (cPGA).

Authors: Nicole Wake, Andrew B. Rosenkrantz, Daniel K. Sodickson, Hersh Chandarana and James S. Wysock

3D printing technology and internet of things prototyping in family practice: building pulse oximeters during COVID-19 pandemic

Family doctors can have an active role in identifying significant population needs and solutions. During the COVID-19 epidemic, patient home monitoring with pulse oximetry has been a key aspect of care of pati...

Authors: Matteo Capobussi and Lorenzo Moja

Low cost 3D printed clamps for external fixator for developing countries: a biomechanical study

External fixation is a mainstream limb reconstruction technique, most often used after a traumatic injury. Due to the high rates of trauma in developing countries, external fixation devices are often utilized ...

Authors: Felix J. Landaeta, Jose Nauaki Shiozawa, Arthur Erdman and Cara Piazza

3D printed bone models in oral and cranio-maxillofacial surgery: a systematic review

This systematic review aimed to evaluate the use of three-dimensional (3D) printed bone models for training, simulating and/or planning interventions in oral and cranio-maxillofacial surgery.

Authors: Matteo Meglioli, Adrien Naveau, Guido Maria Macaluso and Sylvain Catros

Clinical applications of custom 3D printed implants in complex lower extremity reconstruction

Three dimensional printing has greatly advanced over the past decade and has made an impact in several industries. Within the field of orthopaedic surgery, this technology has vastly improved education and adv...

Authors: Rishin J. Kadakia, Colleen M. Wixted, Nicholas B. Allen, Andrew E. Hanselman and Samuel B. Adams

3D printing in critical care: a narrative review

3D printing (3DP) has gained interest in many fields of medicine including cardiology, plastic surgery, and urology due to its versatility, convenience, and low cost. However, critical care medicine, which is ...

Authors: Mina Boshra, Justin Godbout, Jeffrey J. Perry and Andy Pan