Articles

Patient-specific 3D printed and augmented reality kidney and prostate cancer models: impact on patient education

Patient-specific 3D models are being used increasingly in medicine for many applications including surgical planning, procedure rehearsal, trainee education, and patient education. To date, experiences on the ...

Authors: Nicole Wake, Andrew B. Rosenkrantz, Richard Huang, Katalina U. Park, James S. Wysock, Samir S. Taneja, William C. Huang, Daniel K. Sodickson and Hersh Chandarana

Dose calibration of Gafchromic EBT3 film for Ir-192 brachytherapy source using 3D-printed PLA and ABS plastics

3D printing technology has allowed the creation of custom applicators for high dose rate (HDR) brachytherapy, especially for complex anatomy. With conformal therapy comes the need for advanced dosimetric verif...

Authors: Courtney Oare, Christopher Wilke, Eric Ehler, Damien Mathew, David Sterling and Clara Ferreira

Low cost additive manufacturing of microneedle masters

Microneedle patches are arrays of tiny needles that painlessly pierce the skin to deliver medication into the body. Biocompatible microneedles are usually fabricated via molding of a master structure. Microfab...

Authors: Ashley R. Johnson and Adam T. Procopio

Utility of virtual monoenergetic images from spectral detector computed tomography in improving image segmentation for purposes of 3D printing and modeling

One of the key steps in generating three-dimensional (3D) printed models in medicine is segmentation of radiologic imaging. The software tools used for segmentation may be automated, semi-automated, or manual ...

Authors: Elias Kikano, Nils Grosse Hokamp, Leslie Ciancibello, Nikhil Ramaiya, Christos Kosmas and Amit Gupta

Abstracts from the 3dMed Australia Conference 2018

Authors:

3D printing of surgical hernia meshes impregnated with contrast agents: in vitro proof of concept with imaging characteristics on computed tomography

Selected medical implants and other 3D printed constructs could potentially benefit from the ability to incorporate contrast agents into their structure. The purpose of the present study is to create 3D printe...

Authors: David H. Ballard, Udayabhanu Jammalamadaka, Karthik Tappa, Jeffery A. Weisman, Christen J. Boyer, Jonathan Steven Alexander and Pamela K. Woodard

Exploration of time sequential, patient specific 3D heart unlocks clinical understanding

The purpose was to create a time sequential three-dimensional virtual reality model, also referred to as a four-dimensional model, to explore its possible benefit and clinical applications. We hypothesized tha...

Authors: Kylie A. Mena, Kevin P. Urbain, Kevin M. Fahey and Matthew T. Bramlet

Using 3D models in orthopedic oncology: presenting personalized advantages in surgical planning and intraoperative outcomes

Three Dimensional (3D) printed models can aid in effective pre-operative planning by defining the geometry of tumor mass, bone loss, and nearby vessels to help determine the most accurate osteotomy site and th...

Authors: Thipachart Punyaratabandhu, Peter C. Liacouras and Sutipat Pairojboriboon

High-throughput scaffold-free microtissues through 3D printing

Three-dimensional (3D) cell cultures and 3D bioprinting have recently gained attention based on their multiple advantages over two-dimensional (2D) cell cultures, which have less translational potential to rec...

Authors: Christen J. Boyer, David H. Ballard, Mansoureh Barzegar, J. Winny Yun, Jennifer E. Woerner, Ghali E. Ghali, Moheb Boktor, Yuping Wang and J. Steven Alexander

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios

Medical three-dimensional (3D) printing has expanded dramatically over the past three decades with growth in both facility adoption and the variety of medical applications. Consideration for each step required...

Authors: Leonid Chepelev, Nicole Wake, Justin Ryan, Waleed Althobaity, Ashish Gupta, Elsa Arribas, Lumarie Santiago, David H Ballard, Kenneth C Wang, William Weadock, Ciprian N Ionita, Dimitrios Mitsouras, Jonathan Morris, Jane Matsumoto, Andy Christensen, Peter Liacouras…

3D printing for congenital heart disease: a single site’s initial three-yearexperience

3D printing is an ideal manufacturing process for creating patient-matched models (anatomical models) for surgical and interventional planning. Cardiac anatomical models have been described in numerous case st...

Authors: Justin Ryan, Jonathan Plasencia, Randy Richardson, Daniel Velez, John J. Nigro, Stephen Pophal and David Frakes

Material characterization and selection for 3D-printed spine models

The two most popular models used in anatomical training for residents, clinicians, or surgeons are cadavers and sawbones. The former is extremely costly and difficult to attain due to cost, ethical implication...

Authors: John Hao, Raj Nangunoori, Ying Ying Wu, Mabaran Rajaraman, Daniel Cook, Alex Yu, Boyle Cheng and Kenji Shimada

Efficacy of using a 3D printed lumbosacral spine phantom in improving trainee proficiency and confidence in CT-guided spine procedures

Minimally-invasive spine procedures provide targeted, individualized diagnosis and pain management for patients. Competence in these procedures is acquired through experience and training. We created a 3D prin...

Authors: Yi Li, Zhixi Li, Simon Ammanuel, Derrick Gillan and Vinil Shah

Utilizing a low-cost desktop 3D printer to develop a “one-stop 3D printing lab” for oral and maxillofacial surgery and dentistry fields

In the oral and maxillofacial surgery and dentistry fields, the use of three-dimensional (3D) patient-specific organ models is increasing, which has increased the cost of obtaining them. We developed an enviro...

Authors: Takashi Kamio, Kamichika Hayashi, Takeshi Onda, Takashi Takaki, Takahiko Shibahara, Takashi Yakushiji, Takeo Shibui and Hiroshi Kato

Rapid customization system for 3D-printed splint using programmable modeling technique – a practical approach

Traditional splinting processes are skill dependent and irreversible, and patient satisfaction levels during rehabilitation are invariably lowered by the heavy structure and poor ventilation of splints. To ove...

Authors: Jianyou Li and Hiroya Tanaka

Low-cost customized cranioplasty using a 3D digital printing model: a case report

Cranial defects usually occur after trauma, neurosurgical procedures like decompressive craniotomy, tumour resections, infection and congenital defects. The purpose of cranial vault repair is to protect the un...

Authors: Abel De La Peña, Javier De La Peña-Brambila, Juan Pérez-De La Torre, Miguel Ochoa and Guillermo J. Gallardo

Patient-specific neurosurgical phantom: assessment of visual quality, accuracy, and scaling effects

Training in medical education depends on the availability of standardized materials that can reliably mimic the human anatomy and physiology. One alternative to using cadavers or animal bodies is to employ pha...

Authors: Felipe Wilker Grillo, Victor Hugo Souza, Renan Hiroshi Matsuda, Carlo Rondinoni, Theo Zeferino Pavan, Oswaldo Baffa, Helio Rubens Machado and Antonio Adilton Oliveira Carneiro

On the optimization of low-cost FDM 3D printers for accurate replication of patient-specific abdominal aortic aneurysm geometry

There is a potential for direct model manufacturing of abdominal aortic aneurysm (AAA) using 3D printing technique for generating flexible semi-transparent prototypes. A patient-specific AAA model was manufact...

Authors: Michael Chung, Norbert Radacsi, Colin Robert, Edward D. McCarthy, Anthony Callanan, Noel Conlisk, Peter R. Hoskins and Vasileios Koutsos

Feasibility study applying a parametric model as the design generator for 3D–printed orthosis for fracture immobilization

Applying 3D printing technology for the fabrication of custom-made orthoses provides significant advantages, including increased ventilation and lighter weights. Currently, the design of such orthoses is most ...

Authors: Jianyou Li and Hiroya Tanaka

Preoperative planning and tracheal stent design in thoracic surgery: a primer for the 2017 Radiological Society of North America (RSNA) hands-on course in 3D printing

In this work, we provide specific clinical examples to demonstrate basic practical techniques involved in image segmentation, computer-aided design, and 3D printing. A step-by-step approach using United States...

Authors: Leonid Chepelev, Carolina Souza, Waleed Althobaity, Olivier Miguel, Satheesh Krishna, Ekin Akyuz, Taryn Hodgdon, Carlos Torres, Nicole Wake, Amy Alexander, Elizabeth George, Anji Tang, Peter Liacouras, Jane Matsumoto, Jonathan Morris, Andy Christensen…

Creating three dimensional models of Alzheimer’s disease

Alzheimer’s disease prevalence will reach epidemic proportions in coming decades. There is a need for impactful educational materials to help patients, families, medical practitioners, and policy makers unders...

Authors: Matthew Marks, Amy Alexander, Joseph Matsumoto, Jane Matsumoto, Jonathan Morris, Ronald Petersen, Clifford Jack Jr., Tatsuya Oishi and David Jones

Design and fabrication of a 3D–printed oral stent for head and neck radiotherapy from routine diagnostic imaging

Oral stents have been shown to reduce the deleterious effects of head and neck radiotherapy through the displacement of normal tissues away from the areas of high dose irradiation. While these stents are commo...

Authors: Christopher T. Wilke, Mohamed Zaid, Caroline Chung, Clifton D. Fuller, Abdallah S. R. Mohamed, Heath Skinner, Jack Phan, G. Brandon Gunn, William H. Morrison, Adam S. Garden, Steven J. Frank, David I. Rosenthal, Mark S. Chambers and Eugene J. Koay

Application of 3D–printed and patient-specific cast for the treatment of distal radius fractures: initial experience

Distal radius fracture is common in the general population. Fracture management includes a plaster cast, splint and synthetic material cast to immobilise the injured arm. Casting complications are common in th...

Authors: Yan-Jun Chen, Hui Lin, Xiaodong Zhang, Wenhua Huang, Lin Shi and Defeng Wang

3D-printed phantom study for investigating stent abutment during gastroduodenal stent placement for gastric outlet obstruction

Placing a self-expandable metallic stent (SEMS) is safe and effective for the palliative treatment of malignant gastroduodenal (GD) strictures. SEMS abutment in the duodenal wall is associated with increased f...

Authors: Guk Bae Kim, Jung-Hoon Park, Ho-Young Song, Namkug Kim, Hyun Kyung Song, Min Tae Kim, Kun Yung Kim, Jiaywei Tsauo, Eun Jung Jun, Do Hoon Kim and Gin Hyug Lee

Development of a 3D printed device to support long term intestinal culture as an alternative to hyperoxic chamber methods

Most interactions between pathogenic microorganisms and their target host occur on mucosal surfaces of internal organs such as the intestine. In vitro organ culture (IVOC) provides an unique tool for studying ...

Authors: Matheus O. Costa, Roman Nosach and John C.S. Harding

Using computed tomography and 3D printing to construct custom prosthetics attachments and devices

The prosthetic devices the military uses to restore function and mobility to our wounded warriors are highly advanced, and in many instances not publically available. There is considerable research aimed at th...

Authors: Peter C. Liacouras, Divya Sahajwalla, Mark D. Beachler, Todd Sleeman, Vincent B. Ho and John P. Lichtenberger III

Surgical reconstruction of the ossicular chain with custom 3D printed ossicular prosthesis

Conductive hearing loss due to ossicular abnormalities occurs from many causes, including trauma, infection, cholesteatoma, surgery and congenital anomalies. Surgical reconstruction of the ossicular chain is a...

Authors: Jeffrey D. Hirsch, Richard L. Vincent and David J. Eisenman

Anatomic modeling using 3D printing: quality assurance and optimization

The purpose of this study is to provide a framework for the development of a quality assurance (QA) program for use in medical 3D printing applications. An interdisciplinary QA team was built with expertise fr...

Authors: Shuai Leng, Kiaran McGee, Jonathan Morris, Amy Alexander, Joel Kuhlmann, Thomas Vrieze, Cynthia H. McCollough and Jane Matsumoto

Implementation of iterative metal artifact reduction in the pre-planning-procedure of three-dimensional physical modeling

To assess the impact of metal artifact reduction techniques in 3D printing by evaluating image quality and segmentation time in both phantom and patient studies with dental restorations and/or other metal impl...

Authors: Roy P. Marcus, Jonathan M. Morris, Jane M. Matsumoto, Amy E. Alexander, Ahmed F. Halaweish, James A Kelly, Joel G. Fletcher, Cynthia H. McCollough and Shuai Leng

Medical 3D printing: methods to standardize terminology and report trends

Medical 3D printing is expanding exponentially, with tremendous potential yet to be realized in nearly all facets of medicine. Unfortunately, multiple informal subdomain-specific isolated terminological ‘silos...

Authors: Leonid Chepelev, Andreas Giannopoulos, Anji Tang, Dimitrios Mitsouras and Frank J. Rybicki

Accelerated workflow for primary jaw reconstruction with microvascular fibula graft

Major facial defects due to cancer or deformities can be reconstructed through microvascular osteocutaneous flaps. Hereby CAD/CAM workflows offer a possibility to optimize reconstruct and reduce surgical time....

Authors: Elisabeth Goetze, Matthias Gielisch, Maximilian Moergel and Bilal Al-Nawas

Fabrication approaches for the creation of physical models from microscopy data

Three-dimensional (3D) printing has become a useful method of fabrication for many clinical applications. It is also a technique that is becoming increasingly accessible, as the price of the necessary tools an...

Authors: Benjamin L. Cox, Nathan Schumacher, John Konieczny, Issac Reifschneider, Thomas R. Mackie, Marisa S. Otegui and Kevin W. Eliceiri

Maintaining safety and efficacy for 3D printing in medicine

The increased and accelerating utilization of 3D printing in medicine opens up questions regarding safety and efficacy in the use of medical models. The authors recognize an important shift towards point-of-ca...

Authors: Andy Christensen and Frank J. Rybicki

Medical 3D printing for vascular interventions and surgical oncology: a primer for the 2016 radiological society of North America (RSNA) hands-on course in 3D printing

Medical 3D printing holds the potential of transforming personalized medicine by enabling the fabrication of patient-specific implants, reimagining prostheses, developing surgical guides to expedite and transf...

Authors: Leonid Chepelev, Taryn Hodgdon, Ashish Gupta, Aili Wang, Carlos Torres, Satheesh Krishna, Ekin Akyuz, Dimitrios Mitsouras and Adnan Sheikh

A rapid and intelligent designing technique for patient-specific and 3D-printed orthopedic cast

Two point four out of 100 people suffer from one or more fractures in the course of average lifetimes. Traditional casts are featured as cumbersome structures that result in high risk of cutaneous complication...

Authors: Hui Lin, Lin Shi and Defeng Wang

3D printing in medicine of congenital heart diseases

Congenital heart diseases causing significant hemodynamic and functional consequences require surgical repair. Understanding of the precise surgical anatomy is often challenging and can be inadequate or wrong....

Authors: Shi-Joon Yoo, Omar Thabit, Eul Kyung Kim, Haruki Ide, Deane Yim, Anreea Dragulescu, Mike Seed, Lars Grosse-Wortmann and Glen van Arsdell

3D Printed replica of articular fractures for surgical planning and patient consent: a two years multi-centric experience

CT scanning with 3D reconstructed images are currently used to study articular fractures in orthopedic and trauma surgery. A 3D-Printer creates solid objects, starting from a 3D Computer representation.

Authors: Nicola Bizzotto, Ivan Tami, Attilio Santucci, Roberto Adani, Paolo Poggi, Denis Romani, Guilherme Carpeggiani, Filippo Ferraro, Sandro Festa and Bruno Magnan

Additively manufactured medical products – the FDA perspective

Additive manufacturing/3D printing of medical devices is becoming more commonplace, a 3D printed drug is now commercially available, and bioprinting is poised to transition from laboratory to market. Despite t...

Authors: Matthew Di Prima, James Coburn, David Hwang, Jennifer Kelly, Akm Khairuzzaman and Laura Ricles

3D printed ventricular septal defect patch: a primer for the 2015 Radiological Society of North America (RSNA) hands-on course in 3D printing

Hand-held three dimensional models of the human anatomy and pathology, tailored-made protheses, and custom-designed implants can be derived from imaging modalities, most commonly Computed Tomography (CT). Howe...

Authors: Andreas A. Giannopoulos, Leonid Chepelev, Adnan Sheikh, Aili Wang, Wilfred Dang, Ekin Akyuz, Chris Hong, Nicole Wake, Todd Pietila, Philip B. Dydynski, Dimitrios Mitsouras and Frank J. Rybicki

The residual STL volume as a metric to evaluate accuracy and reproducibility of anatomic models for 3D printing: application in the validation of 3D-printable models of maxillofacial bone from reduced radiation dose CT images

The effects of reduced radiation dose CT for the generation of maxillofacial bone STL models for 3D printing is currently unknown. Images of two full-face transplantation patients scanned with non-contrast 320...

Authors: Tianrun Cai, Frank J. Rybicki, Andreas A. Giannopoulos, Kurt Schultz, Kanako K. Kumamaru, Peter Liacouras, Shadpour Demehri, Kirstin M. Shu Small and Dimitris Mitsouras

3D Printing in Medicine: an introductory message from the Editor-in-Chief

Authors: Frank J. Rybicki